Ghrelin receptor binding
Characterised as an agonist at the growth hormone secretagogue receptor, studied in receptor-expressing cell preparations.
- Assessed at GHS-R1a
- Studied in receptor-expressing lines
- Compared against other secretagogues
≥99.5% purityGH SecretagoguesUSA made
Ipamorelin
Selective pentapeptide growth hormone secretagogue. Clean impurity profile by RP-HPLC.
Price per vial
$58/ 10mg
99.5%HPLC
1
- Third-party HPLC + LC-MS
- COA published per lot
- Insulated cold-chain dispatch
- Free shipping over $250
- 20+
- Published studies
- 5
- Amino acid sequence
- 1a
- GHS receptor target
- 2
- Research areas
Figures are illustrative of published preclinical research and are provided for orientation only. They are not claims about this product.
— About this compound
What Ipamorelin is
Ipamorelin is a synthetic pentapeptide growth hormone secretagogue characterised by its selectivity — it is frequently cited as one of the more selective secretagogues in its class. It is supplied lyophilised with a consistently clean impurity profile by RP-HPLC.
- Class
- GH secretagogue
- Residues
- 5 amino acids
- Note
- Selective profile
- Form
- Lyophilised powder
Sequence
- Aib
- His
- DBnal
- DPhe
- Lys
- NH₂
BACKBONE IMPRESSION · NOT A STRUCTURAL MODEL
— MechanismHow Ipamorelin
How Ipamorelin
has been studied.
Signalling pathways examined in preclinical models. Descriptive of published research directions, not claims of effect.
Selectivity profile
A substantial part of the published characterisation concerns what Ipamorelin does not do relative to earlier secretagogues, which is the basis of its reputation for selectivity.
- Profiled against related receptor targets
- Compared with GHRP-class analogs
- Examined in secretory dynamics models
— Uses & applications
What Ipamorelin is researched for
Endocrine
Secretagogue models
Used as a reference standard in preclinical work on growth hormone secretory pathways.
Analytical
Comparative assay
Frequently run alongside other secretagogues as a comparison standard in method development.
Study-reported magnitudes
Representative figures
- GH release selectivity
- 90%
- GHS-R1a binding affinity
- 82%
- Cortisol axis cross-activity
- 12%
- Prolactin cross-activity
- 15%
Illustrative of published preclinical findings. Not a representation of this product’s performance, and not a claim of any effect in humans.
— Third-party verifiedIndependently tested.
Independently tested.
Verifiably pure.
- PASS
HPLC purity
RP-HPLC, 214 nm
- CONFIRMED
Identity
LC-MS
- PASS
Endotoxin (LAL)
Kinetic chromogenic
- PASS
Heavy metals
ICP-MS
- VERIFIED
Net peptide content
Nitrogen analysis
- PASS
Residual solvents
Headspace GC
Certificate of analysis
PASSLot LP-2601-E
RP-HPLC · 214nm2026-01-18
- HPLC purity
- 99.5%
- Identity
- Confirmed by LC-MS
- Endotoxin (LAL)
- < 0.5 EU/mg
- Heavy metals
- Pass
— Full specification
Every field on the label
- Sequence
- Aib-His-DBnal-DPhe-Lys-NH₂
- Molecular formula
- C38H49N9O5
- Molecular weight
- 711.85 g/mol
- CAS / identifier
- 170851-70-4
- Quantity per vial
- 10 mg
- Purity
- 99.5% by RP-HPLC, 214 nm
- Identity
- Confirmed by LC-MS
- Appearance
- White lyophilised cake
- Solubility
- Soluble in bacteriostatic water
- Storage
- -20°C long term, 2-8°C in use
- Endotoxin
- < 0.5 EU/mg
- Heavy metals
- Below limit of quantitation
- Country of origin
- United States
- Lot
- LP-2601-E
- Assay date
- 2026-01-18
Published characterisation focuses on its behaviour at the growth hormone secretagogue receptor relative to its activity at related targets. Researchers commonly select it for that comparatively narrow profile.
Store the sealed vial at −20°C for long-term stability and 2–8°C for short-term handling. Protect from light and avoid repeated freeze-thaw cycles. Compound-specific stability data is printed on the certificate of analysis supplied with the lot.
This material is supplied as a reference standard for in-vitro laboratory research only. It has not been evaluated by the FDA, is not a drug, and is not intended for human or veterinary use. Handling should follow your institution's chemical hygiene plan, including appropriate PPE and documented disposal.
— Cited sources
Published literature
Independent published research relating to this compound. Listed for reference; Lumen Peptides, Inc. is not affiliated with these authors and makes no claims based on their findings.
- [1]
Ipamorelin, the first selective growth hormone secretagogue
Raun K et al. · 1998 · European Journal of Endocrinology
- [2]
Pharmacokinetic-pharmacodynamic modeling of ipamorelin
Gobburu JV et al. · 1999 · Pharmaceutical Research
For laboratory research use only. All compounds listed on this site are sold strictly as reference materials for in-vitro laboratory research conducted by qualified professionals. They are not drugs, foods, cosmetics, or medical devices. They are not intended for human or veterinary consumption, therapeutic use, diagnostic application, or any in-vivo use whatsoever. These statements have not been evaluated by the Food and Drug Administration. By purchasing, you affirm that you are a qualified researcher and that you will comply with all applicable institutional, local, state and federal regulations governing the handling of research chemicals.