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  • 99%+ HPLC PURITY
  • MASS-SPEC CONFIRMED IDENTITY
  • ISO/IEC 17025 LABS
  • COA PUBLISHED PER LOT
  • ENDOTOXIN SCREENED
  • HEAVY METALS PANEL
  • COLD-CHAIN HANDLED
  • US SYNTHESIS & FULFILLMENT
  • SAME-DAY DISPATCH
  • LOT-TRACEABLE TO LABEL
LUMENPEPTIDESLUMEN PEPTIDES
LUMENPEPTIDESMT-210 MG99.1% PURITY · HPLCRESEARCH USE ONLY · NOT FOR HUMAN USELOT LP-2601-D
99.1% purityMelanocortinUSA made

MT-2

Cyclic melanocortin receptor agonist analog. Amber-vialed against photodegradation.

Price per vial

$48/ 10mg

99.1%HPLC
1
  • Third-party HPLC + LC-MS
  • COA published per lot
  • Insulated cold-chain dispatch
  • Free shipping over $250
View this lot’s certificate
30+
Published studies
7
Core ring residues
4
MC receptor subtypes
2
Research areas

Figures are illustrative of published preclinical research and are provided for orientation only. They are not claims about this product.

— About this compound

What MT-2 is

MT-2 is a synthetic cyclic analog of alpha-melanocyte-stimulating hormone. Its cyclic lactam structure confers substantially greater metabolic stability than the linear parent hormone. It is supplied in amber vials because the compound is photosensitive.

Class
Melanocortin analog
Structure
Cyclic lactam
Basis
α-MSH scaffold
Handling
Photosensitive
Sequence
  1. Ac
  2. Nle
  3. cyclo[Asp
  4. His
  5. DPhe
  6. Arg
  7. Trp
  8. Lys]
  9. NH₂
BACKBONE IMPRESSION · NOT A STRUCTURAL MODEL
— Mechanism

How MT-2
has been studied.

Signalling pathways examined in preclinical models. Descriptive of published research directions, not claims of effect.

MC receptors

Melanocortin receptor binding

Characterised against the melanocortin receptor family, with binding profiles studied across MC1R and MC4R in receptor-expressing cell lines.

  • Assessed across MC receptor subtypes
  • Studied in receptor-expressing cell lines
  • Compared against native α-MSH
Cyclisation

Structural stability

The lactam bridge constrains the peptide backbone, which is the structural basis for its resistance to enzymatic degradation relative to the linear hormone.

  • Cyclic lactam constraint
  • Studied in plasma stability preparations
  • Characterised by LC-MS fragmentation
— Uses & applications

What MT-2 is researched for

Receptor pharmacology

Melanocortin binding

Used as a characterised reference ligand in melanocortin receptor binding and selectivity work.

Pigmentation biology

Melanocyte models

Applied in in-vitro melanocyte preparations examining melanogenesis markers.

Study-reported magnitudes

Representative figures

MC1R binding affinity
86%
Melanogenesis marker response
74%
Plasma stability vs α-MSH
92%
MC4R cross-reactivity
48%

Illustrative of published preclinical findings. Not a representation of this product’s performance, and not a claim of any effect in humans.

— Third-party verified

Independently tested.
Verifiably pure.

  • HPLC purity

    RP-HPLC, 214 nm

    PASS
  • Identity

    LC-MS

    CONFIRMED
  • Endotoxin (LAL)

    Kinetic chromogenic

    PASS
  • Heavy metals

    ICP-MS

    PASS
  • Net peptide content

    Nitrogen analysis

    VERIFIED
  • Residual solvents

    Headspace GC

    PASS
Certificate of analysis

Lot LP-2601-D

PASS
RP-HPLC · 214nm2026-01-09
HPLC purity
99.1%
Identity
Confirmed by LC-MS
Endotoxin (LAL)
< 0.5 EU/mg
Heavy metals
Pass
View full certificate
— Full specification

Every field on the label

Sequence
Ac-Nle-cyclo[Asp-His-DPhe-Arg-Trp-Lys]-NH₂
Molecular formula
C50H69N15O9
Molecular weight
1024.18 g/mol
CAS / identifier
121062-08-6
Quantity per vial
10 mg
Purity
99.1% by RP-HPLC, 214 nm
Identity
Confirmed by LC-MS
Appearance
White to pale lyophilised cake
Solubility
Soluble in bacteriostatic water
Storage
-20°C, amber vial, protect from light
Endotoxin
< 0.5 EU/mg
Heavy metals
Below limit of quantitation
Country of origin
United States
Lot
LP-2601-D
Assay date
2026-01-09
— Common questions

About MT-2

Still unsure? Ask the lab — median response under four hours.

MT-2 is photosensitive. Amber glass and light-protected storage prevent photodegradation, which would otherwise show up as a rising impurity profile on reassay.

Store the sealed vial at −20°C for long-term stability and 2–8°C for short-term handling. Protect from light and avoid repeated freeze-thaw cycles. Compound-specific stability data is printed on the certificate of analysis supplied with the lot.

This material is supplied as a reference standard for in-vitro laboratory research only. It has not been evaluated by the FDA, is not a drug, and is not intended for human or veterinary use. Handling should follow your institution's chemical hygiene plan, including appropriate PPE and documented disposal.

— Cited sources

Published literature

Independent published research relating to this compound. Listed for reference; Lumen Peptides, Inc. is not affiliated with these authors and makes no claims based on their findings.

  1. [1]

    Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide

    Dorr RT et al. · 1996 · Life Sciences

  2. [2]

    Melanocortin peptide therapeutics

    Hadley ME, Dorr RT · 2006 · Peptides

For laboratory research use only. All compounds listed on this site are sold strictly as reference materials for in-vitro laboratory research conducted by qualified professionals. They are not drugs, foods, cosmetics, or medical devices. They are not intended for human or veterinary consumption, therapeutic use, diagnostic application, or any in-vivo use whatsoever. These statements have not been evaluated by the Food and Drug Administration. By purchasing, you affirm that you are a qualified researcher and that you will comply with all applicable institutional, local, state and federal regulations governing the handling of research chemicals.

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